More exactly, it suggests that physical activity may reduce the risk of obesity in people with a genetic mutation that predisposes them to high body mass index. According to background information in the study, variations of a particular gene, known as the fat mass and obesity associated (FTO) gene, are widely acknowledged to be linked with a high body mass index. These mutations occur in about 30 percent of European populations and are associated with a 1.75-kilogram (3.9 lb.) increase in body weight.
For the study, researchers at the